Full Metal Alcemist

Edward and Alphonse Elric are two alchemists brothers who search to get the legendary Philosopher's Stone, a powerful object who would allow them to recover their bodies lost in an attempt to bring their mother back to life through alchemy. Being born in the village of Resembool from the country of Amestris ( Amesutorisu), the two brothers lived there with their parents. Their father, Hohenheim, left home for unknown reasons and years later, their mother, Trisha Elric, died of a terminal illness leaving the Elric brothers alone. After their mother's death, Edward becomes determined to bring her back through the use of alchemy, an advanced science in which objects can be created from raw materials. They researched Human Transmutation, a forbidden art in which one attempts to create or modify a human being. However, this attempt failed, ultimately resulting in the loss of Edward's left leg and Alphonse's entire body. In a desperate effort to save his brother, Edward sacrificed his right arm to affix his brother's soul to a suit of armor. Some days later, an alchemist named Roy Mustang visits the Elric brothers, and he tells Edward to become a member of the State Military of the country to find a way to recover their bodies. After that, Edward's left leg and right arm are fitted with two sets of automail, a type of advanced prosthetic limb, created for him by his close family friends Winry Rockbell and her grandmother Pinako.